SCHEMBL5888930

SCHEMBL5888930

C=CCOc1c[c]cc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.48
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
TSHR P16473 2/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GAA P10253 2/20 0.40
POLB P06746 1/20 0.40
LIG1 P18858 1/20 0.39
CYP3A4 P08684 1/20 0.37
CYP2A6 P11509 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 2/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
SETDB1 Q15047 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL21694712 0.81 HPGD (0.55) HPGDCA12CA1CA9TSHR
SCHEMBL5888905 0.81 CYP3A4 (0.44) HPGDCA12CA1CA9TSHR
SCHEMBL4371294 0.79 HPGD (0.56) HPGDCA12CA1CA9TSHR
Ethylene SCHEMBL3362752 0.77 HPGD (0.55) HPGDCA12CA1CA9TSHR
SCHEMBL2255444 0.77 ALDH1A1 (0.41) TSHRMAPTALDH1A1
SCHEMBL9533259 0.77 HTR1B (0.37) HPGDALDH1A1KDM4E
SCHEMBL8681171 0.75 HTR1B (0.46) TSHRGAA
SCHEMBL6041472 0.75 MAPT (0.49) HPGDMAPK1GAAMAPTALDH1A1
SCHEMBL3820950 0.74 HPGD (0.54) HPGDCA12CA1CA9TSHR
SCHEMBL2253601 0.73 HTR1B (0.50) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US claimed