Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84309 | 0.94 | KMT2A (0.38) | HDAC1HDAC11HDAC8HDAC6HDAC3 | |
| SCHEMBL4757636 | 0.83 | HDAC1 (0.39) | HDAC1HDAC11HDAC8HDAC6KCNH2 | |
| SCHEMBL325229 | 0.80 | KMT2A (0.38) | HDAC1HDAC11HDAC8HDAC6HDAC3 | |
| SCHEMBL27459264 | 0.78 | ALDH1A1 (0.37) | KCNH2KMT2ALMNAMAPTPOLB | |
| SCHEMBL84280 | 0.77 | ALDH1A1 (0.41) | KCNH2KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL4756582 | 0.77 | KMT2A (0.40) | HDAC1HDAC11HDAC8HDAC6HDAC3 | |
| SCHEMBL6642474 | 0.76 | KMT2A (0.36) | HDAC1HDAC11HDAC8HDAC6HDAC3 | |
| Fluoride SCHEMBL28515671 | 0.75 | ALDH1A1 (0.40) | KCNH2KMT2ALMNAMAPTNPSR1 | |
| SCHEMBL11199571 | 0.75 | NPC1 (0.44) | HDAC1HDAC11HDAC8HDAC6HDAC3 | |
| SCHEMBL11199615 | 0.75 | NPC1 (0.48) | HDAC1HDAC11HDAC8HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024008805-A1 | HETEROAROMATIC KETONES AND THEIR USE IN RADICAL AND CATIONIC POLYMERIZATION | PHOSUMA PHOTONIC & SUSTAINABLE MATERIALS GMBH (DE) | 2024-01-11 | — | — | WO | disclosed |
| US-6984737-B2 | Di(het)arylaminothiophene derivatives | SIEMENS AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |
| US-20030137240-A1 | Di(het)arylaminothiophene derivatives | OSRAM OLED GMBH (DE) | 2003-07-24 | — | — | US | disclosed |
| JP-2000256352-A | PRODUCTION OF (DIARYLAMINO)THIOPHENE | TOSOH CORP | 2000-09-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030137240-A1 | Di(het)arylaminothiophene derivatives | PTGER4, LTB4R2, ALOX5 | HDAC1 3812/4885HDAC11 3650/4885HDAC8 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.