Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19511558 | 0.81 | GPR35 (0.41) | DAOGPR35KDM4EMEN1ALDH1A1 | |
| SCHEMBL5888342 | 0.74 | DAO (0.40) | DAOGPR35KDM4EMEN1ALDH1A1 | |
| SCHEMBL5889044 | 0.69 | DAO (0.32) | DAO | |
| SCHEMBL16610036 | 0.69 | DAO (0.46) | DAOGPR35KDM4EMEN1ALDH1A1 | |
| SCHEMBL17201685 | 0.67 | DAO (0.45) | DAOGPR35KDM4EMEN1ALDH1A1 | |
| SCHEMBL18701659 | 0.67 | DAO (0.45) | DAOGPR35KDM4EMEN1ALDH1A1 | |
| SCHEMBL4970408 | 0.67 | DAO (0.45) | DAOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL18701754 | 0.66 | DAO (0.63) | DAOGPR35KDM4EMEN1ALDH1A1 | |
| SCHEMBL19511280 | 0.66 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPT | |
| SCHEMBL10987003 | 0.66 | MAPK1 (0.39) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214316-B1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INT LTD (CH) | 2003-05-07 | — | — | EP | claimed |
| US-7052742-B1 | Five membered-ring compounds and utilization thereof in liquid crystal mixtures | CLARIANT INTERNATIONAL LTD. (CH) | 2006-05-30 | — | — | US | disclosed |