SCHEMBL5889002

SCHEMBL5889002

C=CC(C=C)c1ccccc1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
BCL2L1 Q07817 1/20 0.38
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.38
BACE1 P56817 2/20 0.34
DPP4 P27487 1/20 0.34
KMT2A Q03164 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170429 0.79 ALDH1A1 (0.40) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL7105245 0.79 CA12 (0.39) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL8717008 0.79 ALDH1A1 (0.40) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL29206318 0.78 KDM4E (0.41) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL29106788 0.78 ALDH1A1 (0.34) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL8519698 0.75 ALDH1A1 (0.32) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL4508200 0.75 HTR7 (0.38) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL2843781 0.74 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL8627009 0.74 ALDH1A1 (0.39) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL9247570 0.72 HSP90AA1 (0.39) ALDH1A1HSD17B10HPGDBCL2L1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026406-B1 Syndiotactic styrene polymers and process for the production thereof NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-04-11 US disclosed
EP-1283221-A1 SYNDIOTACTIC STYRENE POLYMERS AND PROCESS FOR THE PRODUCTION THEREOF National Institute of Advanced Industrial Science and Technology (JP) 2003-02-12 EP disclosed
WO-2000053649-A1 STYRENIC GRAFT COPOLYMER AND METHOD OF PREPARING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2000-09-14 WO disclosed
EP-0570932-B1 Styrenic block copolymer and process for producing same IDEMITSU KOSAN CO (JP) 1997-07-23 EP disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5554695-A Styrenic copolymer and process for producing same IDEMITSU KOSAN CO. LTD. (JP) 1996-09-10 US disclosed
EP-0511407-B1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN CO (JP) 1996-05-29 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5475061-A High degree of syndiotactic configuration; using alumoxane and transition metal compound catalysts IDEMITSU KOSAN CO., LTD. (JP) 1995-12-12 US disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5418290-A Compatability with other resins, adhesion IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5391626-A Syndiotactic, high performance, compatibility and adhesiveness; molding materials IDEMITSU KOSAN CO., LTD. (JP) 1995-02-21 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0570931-A2 Styrenic polymer, process for producing same and multi-layer material comprising same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed