Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889051 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL5143350 | 0.77 | GABRA1 (0.38) | GABRA1GABRB2LMNAKDM4EALDH1A1 | |
| SCHEMBL9816460 | 0.72 | NQO2 (0.50) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL9229519 | 0.72 | MEN1 (0.51) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL2946940 | 0.70 | GABRA1 (0.35) | GABRA1GABRB2MEN1KMT2AAURKA | |
| SCHEMBL1416395 | 0.70 | TRPM4 (0.41) | MEN1KMT2APOLBMAPTNPC1 | |
| SCHEMBL4410642 | 0.70 | GABRA1 (0.40) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL5888951 | 0.70 | TRPM4 (0.36) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL1396390 | 0.69 | GABRA1 (0.31) | GABRA1GABRB2MEN1KMT2AKDM4E | |
| SCHEMBL472912 | 0.68 | MEN1 (0.42) | GABRA1GABRB2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041388-B1 | Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices | SEMICONDUCTORS GMBH (DE) | 2006-05-09 | — | — | US | claimed |