SCHEMBL5889015

SCHEMBL5889015

C=CCOc1cc[c]c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA9 Q16790 2/20 0.43
HPGD P15428 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP2A6 P11509 1/20 0.40
LIG1 P18858 1/20 0.39
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
ALDH1A1 P00352 2/20 0.35
KDM4E B2RXH2 1/20 0.35
SETDB1 Q15047 1/20 0.35
SLC22A1 O15245 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5889054 0.89 CYP3A4 (0.46) CA12CA1CA9HPGDTSHR
SCHEMBL3820950 0.78 HPGD (0.54) CA12CA1CA9HPGDTSHR
SCHEMBL40509 0.77 ALDH1A1 (0.41) HPGDTSHRMAPK1HSD17B10CYP2A6
SCHEMBL5934194 0.75 MAPT (0.44) TSHRMAPK1LMNACYP1A2HTR1A
SCHEMBL668349 0.75 CNR1 (0.41) TSHRCYP2A6CYP1A2SLC6A4
SCHEMBL27543624 0.75 CLCN2 (0.32)
SCHEMBL3820470 0.74 CYP3A4 (0.57) CA12CA1CA9HPGDTSHR
SCHEMBL668261 0.73 CYP2C9 (0.46) GAACYP1A2SLC6A4L3MBTL1
SCHEMBL7832236 0.73 TLR8 (0.38) TSHRMAPK1HSD17B10GAAALDH1A1
SCHEMBL7082181 0.73 SLC2A1 (0.39) TSHRHSD17B10GAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7041388-B1 Substituted poly(arylene vinylenes), process for their preparation and their use in electroluminescent devices SEMICONDUCTORS GMBH (DE) 2006-05-09 US claimed
EP-3617758-B1 COMPOSITION FOR FORMING OPTICAL WAVEGUIDE WHICH CONTAINS REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL CORP (JP) 2023-08-09 EP disclosed
CN-109154677-B Low viscosity agent for high refractive index polymerizable compound and polymerizable composition containing same 日产化学株式会社 2022-07-05 CN disclosed
US-11333800-B2 Optical waveguide-forming composition which contains reactive silsesquioxane compound NISSAN CHEMICAL CORPORATION (JP) 2022-05-17 US disclosed
CN-109071731-B Polymerizable composition containing reactive phenanthrene ring-containing silsesquioxane compound 日产化学株式会社 2021-08-13 CN disclosed
CN-109153691-B Polymerizable silane compound 日产化学株式会社 2021-07-09 CN disclosed
CN-109196008-B Reactive polysiloxane and polymerizable composition containing same 日产化学株式会社 2021-07-06 CN disclosed
US-10899891-B2 Reactive polysiloxane and polymerizable composition comprising same NISSAN CHEMICAL CORPORATION (JP) 2021-01-26 US disclosed
US-10894800-B2 Polymerizable silane compound NISSAN CHEMICAL CORPORATION (JP) 2021-01-19 US disclosed
EP-3466956-B1 POLYMERIZABLE SILANE COMPOUND NISSAN CHEMICAL CORP (JP) 2020-12-09 EP disclosed
EP-3327049-A1 REACTIVE SILSESQUIOXANE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING AROMATIC VINYL COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-05-30 EP disclosed
US-20180079849-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-03-22 US disclosed
EP-3281959-A1 POLYMERIZABLE RESIN COMPOSITION CONTAINING REACTIVE SILSESQUIOXANE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2018-02-14 EP disclosed
EP-0534257-B1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS (JP) 1997-03-12 EP disclosed
EP-0524419-B1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS (JP) 1995-09-06 EP disclosed
US-5391806-A A storage stable chromogens as color-developing agent or stabilizers MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-02-21 US disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed
US-5270281-A Chromogenic compound MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-12-14 US disclosed
EP-0534257-A1 Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
EP-0524419-A1 Heat-sensitive recording materials and phenol compounds MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10894800-B2 Polymerizable silane compound PCNA, ARL1, CCNE1 CA12 4163/4885CA1 3279/4885CA9 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.