Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003156 | 0.72 | ALDH1A1 (0.39) | NPC1ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL11515586 | 0.71 | NPC1 (0.36) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL29764 | 0.68 | NPC1 (0.52) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12982405 | 0.66 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12982161 | 0.66 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL11997754 | 0.66 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL120939 | 0.66 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12170048 | 0.66 | NPC1 (0.50) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12887829 | 0.65 | ERN1 (0.46) | NPC1ALDH1A1HSD17B10MAPTGFER | |
| SCHEMBL12929391 | 0.64 | ALDH1A1 (0.43) | NPC1ALDH1A1HSD17B10MAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105545-B2 | N-p-propargyloxyphenethyl-thioacetic acid amides | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| US-20040127739-A1 | Novel n-p-propargyloxyphenethyl-thioacetic acid amides | SYNGENTA CROP PROTECTION, INC. | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127739-A1 | Novel n-p-propargyloxyphenethyl-thioacetic acid amides | O60361, OGA, GRHPR | NPC1 1184/4885ALDH1A1 924/4885HSD17B10 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.