SCHEMBL5890133

SCHEMBL5890133

CCCC1=Cc2c(-c3ccccc3-c3cccc4ccccc34)cccc2C1[Zr](C1C(CCC)=Cc2c(-c3ccccc3-c3cccc4ccccc34)cccc21)[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.32
HTR7 P34969 1/20 0.31
SLC6A4 P31645 2/20 0.31
DRD2 P14416 1/20 0.31
CNR1 P21554 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5582112 0.99 ALOX15 (0.32) ALOX15HTR7SLC6A4DRD2CNR1
SCHEMBL5890351 0.93 CNR1 (0.34) ALOX15HTR7SLC6A4DRD2CNR1
SCHEMBL16175630 0.89 KDM4E (0.32) ALOX15HTR7SLC6A4DRD2
SCHEMBL696086 0.86 CNR1 (0.33) ALOX15HTR7CNR1
SCHEMBL7627579 0.85 SLC6A4 (0.33) ALOX15HTR7SLC6A4DRD2CNR1
SCHEMBL5890508 0.85 NPC1 (0.32)
SCHEMBL5890979 0.84
SCHEMBL5890977 0.84
SCHEMBL540842 0.84 HTR7 (0.33) ALOX15HTR7SLC6A4DRD2CNR1
SCHEMBL5890700 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122498-B2 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-10-17 US disclosed