Glutarate

Glutarate

SCHEMBL589023

C=CC(N)=O.N.O=C(O)CCCC(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.55
ALDH1A1 P00352 2/20 0.55
FGFR4 P22455 1/20 0.55
SLC22A6 Q4U2R8 1/20 0.55
ABCC4 O15439 1/20 0.48
MAPT P10636 1/20 0.48
LMNA P02545 4/20 0.48
BLM P54132 3/20 0.46
KMT2A Q03164 3/20 0.46
THRB P10828 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GABRR3 A8MPY1 1/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
HDAC3 O15379 1/20 0.46
GABBR2 O75899 1/20 0.46
CYP1A2 P05177 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRG2 P18507 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL28935910 0.97 TSHR (0.58) TSHRALDH1A1FGFR4SLC22A6ABCC4
Succinic Acid SCHEMBL28213422 0.87 TSHR (0.65) TSHRALDH1A1FGFR4SLC22A6ABCC4
Succinic Acid SCHEMBL28443304 0.87 TSHR (0.65) TSHRALDH1A1FGFR4SLC22A6ABCC4
Valeric Acid SCHEMBL27574605 0.84 AKR1B1 (0.56) TSHRALDH1A1SLC22A6MAPTLMNA
Acrylamide SCHEMBL28776294 0.84 GPR84 (0.62) TSHRALDH1A1FGFR4SLC22A6ABCC4
Hexanoate SCHEMBL8061804 0.82 AKR1B1 (0.67) TSHRALDH1A1SLC22A6MAPTLMNA
Glutarate SCHEMBL28241209 0.81 SLC22A6 (0.65) TSHRALDH1A1SLC22A6ABCC4MAPT
Adipic Acid SCHEMBL8010920 0.81 ABCC4 (0.45) TSHRALDH1A1FGFR4SLC22A6ABCC4
Heptanoate SCHEMBL22499917 0.81 GPR84 (0.68) TSHRALDH1A1SLC22A6MAPTLMNA
Dodecanoate SCHEMBL20555060 0.81 GPR84 (0.68) TSHRALDH1A1SLC22A6MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114819-B2 Polymers for oilfield applications BAKER HUGHES INCORPORATED (US) 2012-02-14 US disclosed
US-20100105580-A1 Polymers For Oilfield Applications BJ SERVICES COMPANY (US) 2010-04-29 US disclosed