Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28213422 | 1.00 | TSHR (0.65) | TSHRALDH1A1FGFR4LMNAEGLN1 | |
| Succinic Acid SCHEMBL29045660 | 0.92 | TSHR (0.55) | TSHRALDH1A1FGFR4LMNAEGLN1 | |
| Glutarate SCHEMBL28935910 | 0.89 | TSHR (0.58) | TSHRALDH1A1FGFR4LMNANFKB1 | |
| Levulinic Acid SCHEMBL6521215 | 0.88 | LMNA (0.64) | TSHRALDH1A1FGFR4LMNAEGLN1 | |
| Glutarate SCHEMBL589023 | 0.87 | TSHR (0.55) | TSHRALDH1A1FGFR4LMNANFKB1 | |
| R-Chloropropionate SCHEMBL29204175 | 0.85 | TSHR (0.52) | TSHRALDH1A1FGFR4LMNAEGLN1 | |
| Butyric Acid SCHEMBL27803000 | 0.85 | FFAR3 (0.62) | TSHRALDH1A1FGFR4NFKB1BLM | |
| Acrylamide SCHEMBL28209083 | 0.84 | TSHR (0.92) | TSHRALDH1A1FGFR4LMNAEGLN1 | |
| Malonic Acid SCHEMBL2437426 | 0.82 | TSHR (0.65) | TSHRALDH1A1FGFR4LMNANFKB1 | |
| Acrylamide SCHEMBL1417837 | 0.82 | TSHR (0.65) | TSHRALDH1A1FGFR4LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115012234-B | Deflocculating leveling agent for reactive dyeing of reuse water and preparation method thereof | 苏州联胜化学有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-115012234-B | Deflocculating leveling agent for reactive dyeing of reuse water and preparation method thereof | 苏州联胜化学有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-111378161-A | Energy absorption method and application thereof | 翁秋梅 | 2020-07-07 | — | — | CN | disclosed |