SCHEMBL5890887

SCHEMBL5890887

Cc1cc(C)c(C)c(-c2cccc3c2C=C(c2ccccc2)C3[Hf](C2C(c3ccccc3)=Cc3c(-c4cc(C)cc(C)c4C)cccc32)[SiH](C)C)c1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MCOLN3 Q8TDD5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5890127 0.88
SCHEMBL5890209 0.86 EDNRB (0.31) SMN1; SMN2
SCHEMBL5890883 0.84
SCHEMBL5890600 0.81
SCHEMBL5889863 0.81
SCHEMBL5890368 0.80 LMNA (0.30) LMNASMN1; SMN2MCOLN3
SCHEMBL8617479 0.79 ALDH1A1 (0.35) SMN1; SMN2
SCHEMBL5890778 0.79
SCHEMBL5890313 0.78
SCHEMBL5890669 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122498-B2 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-10-17 US disclosed