Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11401927 | 0.80 | PKM (0.43) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL11401924 | 0.78 | PKM (0.39) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL7090829 | 0.76 | PKM (0.40) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL14499239 | 0.75 | KMT2A (0.45) | PKMTHRBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL13205219 | 0.75 | PKM (0.39) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL10420886 | 0.74 | HTT (0.43) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL14593304 | 0.74 | PKM (0.79) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL7722774 | 0.72 | MEN1 (0.52) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL16589953 | 0.71 | PKM (0.54) | PKMTHRBMEN1KMT2AMAPT | |
| SCHEMBL9181204 | 0.70 | MEN1 (0.50) | PKMTHRBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091203-B2 | Imidazo[1,3,5]triazinones and their use | BAYER HEALTHCARE AG (DE) | 2006-08-15 | — | — | US | disclosed |
| US-20050043303-A1 | Novel imidazo[1,3,5]triazinones and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-24 | — | — | US | disclosed |
| US-20050043303-A1 | Novel imidazo[1,3,5]triazinones and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-24 | — | — | US | disclosed |
| US-20050043303-A1 | Novel imidazo[1,3,5]triazinones and their use | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-24 | — | — | US | disclosed |
| US-6803365-B2 | INHIBITORS OF CYCLIC GMP METABOLIZING PHOSPHODIESTERASES FOR TREATMENT OF UROGENITAL DISORDERS | BAYER AKTLENGESELLSCHAFT (DE) | 2004-10-12 | — | — | US | disclosed |
| US-20030195210-A1 | Novel imidazo[1,3,5]triazinones and the use thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2003-10-16 | — | — | US | disclosed |
| CN-1434825-A | Imidazo [1,3,5] triazinones and uses thereof | BAYER AG (DE) | 2003-08-06 | — | — | CN | disclosed |
| EP-1244673-A2 | NOVEL IMIDAZO 1,3,5]TRIAZINONES AND THE USE THEREOF | Bayer Aktiengesellschaft (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047928-A2 | IMIDAZO 1,3,5 TRIAZINONES AND THE USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043303-A1 | Novel imidazo[1,3,5]triazinones and their use | PDE7A, PDE3A, PDE4A | PKM 1201/4885THRB 2847/4885MEN1 4014/4885 |
| US-20030195210-A1 | Novel imidazo[1,3,5]triazinones and the use thereof | PDE3A, PDE5A, PDE3B | PKM 762/4885THRB 2054/4885MEN1 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.