Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw-695634 SCHEMBL29403521 | 0.93 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL5891100 | 0.93 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL5891791 | 0.93 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891717 | 0.93 | SLC2A1 (0.63) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891794 | 0.92 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL5891387 | 0.92 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| Gw-695634 SCHEMBL5891789 | 0.92 | SLC2A1 (0.61) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891404 | 0.92 | SLC2A1 (0.62) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891486 | 0.92 | SLC2A1 (0.60) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 | |
| SCHEMBL5891824 | 0.91 | SLC2A1 (0.59) | SLC2A1KCNH2TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995283-B2 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-07 | — | — | US | disclosed |
| US-20060009651-A1 | Benzophenones as inhibitors of reverse transcriptase | CHAN JOSEPH H | 2006-01-12 | — | — | US | disclosed |
| US-20040122064-A1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION | 2004-06-24 | — | — | US | disclosed |
| EP-1363877-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SmithKline Beecham Corporation (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070470-A2 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009651-A1 | Benzophenones as inhibitors of reverse transcriptase | POLRMT, ELL, POLR2A | SLC2A1 3333/4885KCNH2 4082/4885TP53 2233/4885 |
| US-20040122064-A1 | Benzophenones as inhibitors of reverse transcriptase | POLRMT, ELL, POLR2A | SLC2A1 3333/4885KCNH2 4082/4885TP53 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.