Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | EDNRA | P25101 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21436903 | 0.89 | L3MBTL1 (0.58) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL24983833 | 0.86 | PTGER1 (0.60) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL30141251 | 0.86 | PTGER1 (0.60) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL11817706 | 0.85 | PDE4D (0.52) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL28126089 | 0.84 | MAPT (0.59) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL11113784 | 0.84 | FOLH1 (0.46) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL28361495 | 0.83 | MAPT (0.57) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL21436784 | 0.82 | PTPN1 (0.58) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL30141088 | 0.82 | TDP1 (0.56) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 | |
| SCHEMBL24983831 | 0.82 | TDP1 (0.56) | L3MBTL1MAPTTDP1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7135500-B2 | Dihydroxymethylphenyl derivatives, processes for preparing them, and their use as pharmaceuticals | BOEHRINGER INGELHEIM PHARMA GMBH & CO KG (DE) | 2006-11-14 | — | — | US | disclosed |
| EP-1562892-A1 | NOVEL DIHYDROXY-METHYLPHENYL DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-08-17 | — | — | EP | disclosed |
| US-20040138307-A1 | Dihydroxymethylphenyl derivatives, processes for preparing them, and their use as pharmaceuticals | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | US | disclosed |
| WO-2004046083-A1 | NOVEL DIHYDROXY-METHYLPHENYL DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-06-03 | — | — | WO | disclosed |
| US-4042713-A | SYMPATHOMIMETIC | BOEHRINGER INGELHEIM GMBH (DT) | 1977-08-16 | — | — | US | disclosed |
| US-3969410-A | SYMPATHOMIMETICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-07-13 | — | — | US | disclosed |
| US-3966814-A | PERIPHERAL VASODILATORS, ANTIHISTAMINES, SPASMOLYTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138307-A1 | Dihydroxymethylphenyl derivatives, processes for preparing them, and their use as pharmaceuticals | CYP1A1, CYP24A1, CYP4B1 | L3MBTL1 4618/4885MAPT 4253/4885TDP1 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.