Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099834 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| SCHEMBL8194 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL3439030 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Hydrogen Sulfide SCHEMBL29184282 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Water SCHEMBL28824188 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL3710107 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| Hydrochloric Acid SCHEMBL3704751 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| SCHEMBL28519048 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| SCHEMBL29592061 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 | |
| SCHEMBL29095245 | 0.71 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, TUBB6, DNMT1 | ALDH1A1 385/4885MAPT 1322/4885KDM4E 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.