Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 5/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5894788 | 0.88 | CYP3A4 (0.41) | CYP1A1CYP1B1CYP1A2RAD52BCHE | |
| SCHEMBL9625282 | 0.80 | MAPK1 (0.42) | CYP1A1CYP1B1RAD52BCHEACHE | |
| SCHEMBL1412043 | 0.77 | CYP2A6 (0.52) | CYP1A2ACHEKDM4EL3MBTL1CYP2A6 | |
| SCHEMBL754022 | 0.76 | ACHE (0.46) | BCHEACHEGPR84NQO1 | |
| Hydrochloric Acid SCHEMBL1204605 | 0.75 | CYP2A6 (0.50) | CYP1A2ACHEKDM4EL3MBTL1CYP2A6 | |
| SCHEMBL22093950 | 0.75 | CYP2A6 (0.55) | CYP1A2ACHEKDM4EL3MBTL1CYP2A6 | |
| SCHEMBL30853167 | 0.75 | CYP2A6 (0.55) | CYP1A2ACHEKDM4EL3MBTL1CYP2A6 | |
| Hydrochloric Acid SCHEMBL6434858 | 0.74 | CYP2A6 (0.53) | CYP1A2ACHEKDM4EL3MBTL1CYP2A6 | |
| SCHEMBL22396479 | 0.73 | ACHE (0.35) | CYP1A2RAD52BCHEACHECYP3A4 | |
| SCHEMBL16431790 | 0.73 | AXL (0.38) | BCHEACHECYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156485-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, TUBB6, DNMT1 | CYP1A1 174/4885CYP1B1 58/4885CYP1A2 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.