Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MPI | P34949 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467361 | 1.00 | NQO2 (0.59) | NQO2TRPM4KDM4EMEN1ALDH1A1 | |
| SCHEMBL8196720 | 0.93 | NQO2 (0.67) | NQO2TRPM4KDM4EMEN1ALDH1A1 | |
| SCHEMBL312189 | 0.88 | ESR1 (0.67) | NQO2TRPM4HSD17B1HSD17B2ESR1 | |
| SCHEMBL15998719 | 0.84 | NQO2 (0.52) | NQO2TRPM4ALDH1A1HSD17B1HSD17B2 | |
| SCHEMBL7527606 | 0.84 | NQO2 (0.52) | NQO2TRPM4HSD17B1HSD17B2ESR1 | |
| SCHEMBL11883070 | 0.84 | ALOX5 (0.52) | NQO2TRPM4HSD17B1HSD17B2ESR1 | |
| SCHEMBL15998721 | 0.81 | CA12 (0.53) | NQO2TRPM4KDM4EMEN1ALDH1A1 | |
| SCHEMBL8172910 | 0.80 | AKR1B1 (0.44) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL312277 | 0.80 | SMN1; SMN2 (0.53) | NQO2KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL14417357 | 0.79 | HSD17B1 (0.79) | KDM4EHSD17B1HSD17B2ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | claimed |
| US-12163968-B2 | Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers | BIO-RAD LABORATORIES, INC. (US) | 2024-12-10 | — | — | US | claimed |
| CN-101781179-B | Method for preparing 1,2-naphthoquinone compound | CHINA GATEWAY PHARMACEUTICAL DEV SHANGHAI CO LTD | 2014-01-29 | — | — | CN | claimed |
| CN-101619016-B | Method for synthesizing polysubstitution 3-phenyl-1-naphthol | UNIV ZHEJIANG | 2012-08-01 | — | — | CN | claimed |
| CN-101781179-A | Method for preparing 1,2-naphthoquinone compound | CHINA GATEWAY PHARMA PRODUCTS | 2010-07-21 | — | — | CN | claimed |
| CN-101619016-A | Method for synthesizing polysubstitution 3-phenyl-1-naphthol | UNIV ZHEJIANG | 2010-01-06 | — | — | CN | claimed |
| EP-4567515-A2 | COMPOSITION COMPRISING NAPHTHOPYRAN PHOTOSWITCHABLE PHOTOINITIATORS AND THIOLS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION | Xolo GmbH (DE) | 2025-06-11 | — | — | EP | disclosed |
| US-20250179222-A1 | COMPOSITION COMPRISING NAPHTHOPYRAN PHOTOSWITCHABLE PHOTOINITIATORS AND THIOLS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION | XOLO GMBH (DE) | 2025-06-05 | — | — | US | disclosed |
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-119219550-A | Reduction method of carboxylic ester compound | 云南大学 | 2024-12-31 | — | — | CN | disclosed |
| US-12163968-B2 | Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers | BIO-RAD LABORATORIES, INC. (US) | 2024-12-10 | — | — | US | disclosed |
| EP-4208021-A1 | PREPARATION OF NUCLEATED RBC (NRBC) ANALOGS FOR USE AS REFERENCE HEMATOLOGY CONTROLS IN AUTOMATED HEMATOLOGY ANALYZERS | Bio-Rad Laboratories, Inc. (US) | 2023-07-12 | — | — | EP | disclosed |
| CN-116097093-A | Preparation of Nucleated RBC (NRBC) analogs for use as reference blood controls in automated blood analyzers | 生物辐射实验室股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL LIMITED (IE) | 2002-11-21 | — | — | US | disclosed |
| US-6478989-B1 | Aromatic substituted naphthopyrans | TRANSITIONS OPTICAL, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1017690-B1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | PPG IND OHIO INC (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-1017690-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | PPG Industries Ohio, Inc. (US) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015519-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TYR, B3GNT2, PAH | NQO2 304/4885TRPM4 2893/4885KDM4E 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.