Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5896828 | 1.00 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5896836 | 1.00 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5895406 | 0.92 | SPHK2 (0.53) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5895427 | 0.92 | SPHK2 (0.53) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5895422 | 0.92 | SPHK2 (0.53) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5897351 | 0.86 | KMT2A (0.56) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5897344 | 0.86 | KMT2A (0.56) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5897338 | 0.86 | KMT2A (0.56) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5896067 | 0.83 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5896045 | 0.83 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041690-B2 | Inhibitors of HCV NS5B polymerase | PHARMACIA & UPJOHN COMPANY, LLC (US) | 2006-05-09 | — | — | US | disclosed |