Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.59 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PLD2 | O14939 | 1/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889578 | 0.94 | HTR2C (0.61) | HTR2CHRH3HRH4NHERF1ACKR3 | |
| SCHEMBL5889693 | 0.82 | HRH4 (0.56) | HTR2CHRH3HRH4ACKR3SYK | |
| SCHEMBL5677746 | 0.82 | ITGB3 (0.59) | NHERF1ITGB3ITGA2B | |
| SCHEMBL5896620 | 0.81 | KDM4E (0.50) | NHERF1PLD2PLD1EGFRPIK3CA | |
| SCHEMBL5889537 | 0.80 | KDM4E (0.51) | NHERF1PLD2PLD1EGFRPIK3CA | |
| SCHEMBL5896655 | 0.80 | KDM4E (0.51) | NHERF1PLD2PLD1EGFRPIK3CA | |
| SCHEMBL5889476 | 0.78 | KDM4E (0.61) | NHERF1ITGB3ITGA2BALOX15 | |
| SCHEMBL8205586 | 0.78 | NHERF1 (0.68) | HRH3NHERF1PLD2PLD1EGFR | |
| SCHEMBL5889592 | 0.78 | ITGB3 (0.50) | NHERF1PLD2PLD1EGFRPIK3CA | |
| SCHEMBL5889645 | 0.78 | KDM4E (0.46) | NHERF1PLD2PLD1EGFRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | claimed |
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | HTR2C 4212/4885HRH3 1724/4885HRH4 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.