Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889621 | 0.91 | HRAS (0.54) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL5677699 | 0.90 | HRAS (0.50) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL5889846 | 0.89 | HRAS (0.54) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL5896881 | 0.88 | HRAS (0.51) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL6489771 | 0.81 | HRAS (0.47) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL5680304 | 0.80 | ITGB3 (0.40) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL6486747 | 0.78 | HRAS (0.46) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL5896786 | 0.77 | HRH3 (0.44) | HRASESR1ESR2 | |
| SCHEMBL5680308 | 0.76 | HRAS (0.38) | HRASESR1ESR2ITGB3ITGA2B | |
| SCHEMBL6779947 | 0.76 | HRAS (0.52) | HRASESR1ESR2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |