Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.40 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 3/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648374 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL2648159 | 0.73 | GCGR (0.68) | ALDH1A1MAPTALOX15MAPK1GCGR | |
| SCHEMBL5897234 | 0.70 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL12643575 | 0.66 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL20254477 | 0.66 | PTPN5 (0.53) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL1719679 | 0.66 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL24862470 | 0.64 | BPTF (0.62) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL1719562 | 0.63 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL2658305 | 0.61 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL12882448 | 0.61 | BPTF (0.49) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060035958-A1 | Method of treating diabetes and related conditions | MERCK & CO., INC. | 2006-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035958-A1 | Method of treating diabetes and related conditions | GLP1R, GPR119, GCGR | ALDH1A1 2972/4885MAPT 4230/4885MEN1 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.