SCHEMBL5897167

SCHEMBL5897167

CN1CCC(=O)N(C)C1=O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.44
BRD2 P25440 1/20 0.44
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158498 0.80
SCHEMBL9020969 0.80
SCHEMBL17433536 0.77 BRD4 (0.68) BRD4BRD2GAASMN1; SMN2
SCHEMBL24400455 0.75 BRD4 (0.36) BRD4BRD2
SCHEMBL2235528 0.75 BRD4 (0.41) BRD4BRD2GAASMN1; SMN2
SCHEMBL27030667 0.72 PLA2G7 (0.36) BRD4BRD2GSK3AGSK3B
SCHEMBL22070 0.72
SCHEMBL17324575 0.72 GAA (0.42) BRD4BRD2GAA
SCHEMBL13684324 0.72 SMN1; SMN2 (0.41) BRD4BRD2GAASMN1; SMN2
SCHEMBL6362000 0.72 CHRM2 (0.33) BRD4BRD2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016103280-A1 STEROID-CHITOSAN KETIMINE NANOPARTICLES FOR ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-06-30 WO claimed
US-20240216513-A1 FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE NOVARTIS AG (CH) 2024-07-04 US disclosed
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF XIZANG HAISCO PHARMACEUTICALS CO., LTD. (CN) 2023-11-09 US disclosed
EP-3271353-A1 3-(4-ETHYNYLPHENYL)HEXAHYDROPYRIMIDIN-2,4-DIONE DERIVATIVES AS MODULATORS OF MGLUR4 F. Hoffmann-La Roche AG (CH) 2018-01-24 EP disclosed
EP-1317013-B1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEM CORP (JP) 2017-03-15 EP disclosed
WO-2016146600-A1 3-(4-ETHYNYLPHENYL)HEXAHYDROPYRIMIDIN-2,4-DIONE DERIVATIVES AS MODULATORS OF MGLUR4 F. HOFFMANN-LA ROCHE AG (CH) 2016-09-22 WO disclosed
US-20130149281-A1 ORGANIC COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2013-06-13 US disclosed
US-8445527-B2 Organic compounds and their uses NOVARTIS AG (CH) 2013-05-21 US disclosed
US-7727583-B2 Method for the production of structured surfaces BASF AKTIENGESELLSCHAFT (DE) 2010-06-01 US disclosed
US-7727583-B2 Method for the production of structured surfaces BASF AKTIENGESELLSCHAFT (DE) 2010-06-01 US disclosed
US-6942948-B2 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2005-09-13 US disclosed
US-20030165733-A1 Nonaqueous electrolyte solution and secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2003-09-04 US disclosed
EP-1317013-A1 NON-AQUEOUS ELECTROLYTE AND SECONDARY CELL USING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2003-06-04 EP disclosed
US-5578633-A VASOPRESSIN AND OXYTOCIN ANTAGONISTS SANOFI (FR) 1996-11-26 US disclosed
US-5481005-A N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present SANOFI (FR) 1996-01-02 US disclosed
US-5397801-A Affinity for vasopressin and ocytocin receptors; disorders of nervous, cardiovascular and gastrointestinal systems SANOFI (FR) 1995-03-14 US disclosed
EP-0403366-B1 Cyclomalto-oligosaccharide derivatives and processes for their preparation COMMISSARIAT ENERGIE ATOMIQUE (FR) 1995-02-22 EP disclosed
US-5338755-A Have affinity for vasopressin and ocytocin receptors; intermediates for drugs that act on central nervous system ELF SANOFI (FR) 1994-08-16 US disclosed
EP-0403366-A2 Cyclomalto-oligosaccharide derivatives and processes for their preparation COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-12-19 EP disclosed
US-4791106-A 1-Carbacephalosporin antibiotics ELI LILLY AND COMPANY (US) 1988-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF AR, CYP17A1, KLK3 BRD4 3246/4885BRD2 3022/4885GAA 941/4885
US-20130149281-A1 ORGANIC COMPOUNDS AND THEIR USES OAT, HAVCR2, CPT1A BRD4 1871/4885BRD2 3445/4885GAA 56/4885
US-20240216513-A1 FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE FASN, FABP1, SCD BRD4 2483/4885BRD2 1599/4885GAA 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.