Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGAV | P06756 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502102 | 0.84 | KDM4E (0.55) | GRIN2BRAB9ASMN1; SMN2NPC1ITGB3 | |
| SCHEMBL2511796 | 0.83 | HTR2B (0.73) | HTR2BGRIN2BUSP30 | |
| SCHEMBL8139051 | 0.81 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL1598709 | 0.79 | RAB9A (0.52) | RAB9ASMN1; SMN2NPC1GSK3AGSK3B | |
| SCHEMBL1598711 | 0.79 | RAB9A (0.52) | RAB9ASMN1; SMN2NPC1GSK3AGSK3B | |
| SCHEMBL4490880 | 0.78 | PDGFRB (0.58) | RAB9ASMN1; SMN2NPC1GSK3AGSK3B | |
| Trifluoroacetic Acid SCHEMBL4527538 | 0.78 | PDGFRB (0.51) | RAB9ASMN1; SMN2NPC1GSK3AGSK3B | |
| SCHEMBL9383756 | 0.78 | NPC1 (0.53) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL5025659 | 0.77 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1GSK3AGSK3B | |
| SCHEMBL5025662 | 0.77 | SMN1; SMN2 (0.51) | RAB9ASMN1; SMN2NPC1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125883-B1 | Integrin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2006-10-24 | — | — | US | disclosed |