Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898416 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL5898326 | 0.96 | — | — | |
| SCHEMBL340694 | 0.77 | TGFBR1 (0.47) | — | |
| Hydrochloric Acid SCHEMBL4442289 | 0.75 | TGFBR1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL28412043 | 0.75 | TGFBR1 (0.46) | — | |
| SCHEMBL7520516 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL411710 | 0.73 | TGFBR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL29001088 | 0.73 | — | — | |
| Trimethylammonium SCHEMBL27544246 | 0.72 | TGFBR1 (0.43) | — | |
| Ammonia Solution, Strong SCHEMBL9421874 | 0.71 | CYP2C9 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049350-B2 | Polymerizable compound, polymerizable composition and cured product containing the compound | SHOWA DENKO K.K. (JP) | 2006-05-23 | — | — | US | disclosed |
| US-20040235980-A1 | Polymerizable compound, polymerizable composition and cured product containing the compound | SHOWA DENKO K.K. (JP) | 2004-11-25 | — | — | US | disclosed |
| WO-2003010124-A1 | POLYMERIZABLE COMPOUND, polymeRIZABLE COMPOSITION AND CURED PRODUCT CONTAINING THE COMPOUND | SHOWA DENKO K. K. (JP) | 2003-02-06 | — | — | WO | disclosed |