Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4442289 | 0.98 | TGFBR1 (0.46) | TGFBR1TDP1LAP3RXFP1 | |
| Hydrochloric Acid SCHEMBL28412043 | 0.98 | TGFBR1 (0.46) | TGFBR1TDP1LAP3RXFP1 | |
| SCHEMBL340694 | 0.96 | TGFBR1 (0.47) | TGFBR1TDP1LAP3RXFP1 | |
| Trimethylammonium SCHEMBL27544246 | 0.90 | TGFBR1 (0.43) | TGFBR1TDP1LAP3 | |
| Hydrochloric Acid SCHEMBL28634771 | 0.78 | TGFBR1 (0.43) | TGFBR1TDP1 | |
| Hydrochloric Acid SCHEMBL5898326 | 0.78 | — | — | |
| SCHEMBL4563862 | 0.77 | TGFBR1 (0.42) | TGFBR1 | |
| Hydrochloric Acid SCHEMBL29001088 | 0.76 | — | — | |
| SCHEMBL6240724 | 0.76 | TGFBR1 (0.41) | TGFBR1LAP3 | |
| SCHEMBL27876214 | 0.76 | TGFBR1 (0.44) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332779-A | Phosphoric acid filtration process | AMERICAN CYANAMID COMPANY (US) | 1982-06-01 | — | — | US | claimed |
| EP-4012478-A1 | FORMING MOLD FOR ENDOSCOPE HOOD | Seed Co., Ltd. (JP) | 2022-06-15 | — | — | EP | disclosed |
| CN-111051965-B | Ophthalmic lenses and imaging methods using ophthalmic lenses | 株式会社实瞳 | 2022-03-25 | — | — | CN | disclosed |
| EP-2397114-B1 | RING-SHAPED DEVICE | SENJU PHARMA CO (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3677950-A1 | OPHTHALMIC LENS AND IMAGING METHOD USING OPHTHALMIC LENS | Seed Co., Ltd. (JP) | 2020-07-08 | — | — | EP | disclosed |
| CN-111051965-A | Ophthalmic lenses and imaging methods using ophthalmic lenses | 株式会社实瞳 | 2020-04-21 | — | — | CN | disclosed |
| US-9486362-B2 | Ring-shaped device | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20120022473-A1 | RING-SHAPED DEVICE | SEED CO., LTD. (JP) | 2012-01-26 | — | — | US | disclosed |
| CN-102316833-A | Ring device | SENJU PHARMA CO | 2012-01-11 | — | — | CN | disclosed |
| US-20080058243-A1 | MULTIPHASE LAUNDRY DETERGENT AND CLEANING PRODUCT SHAPED BODIES HAVING NONCOMPRESSED PARTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20040199018-A1 | Bridged p-phenylenediamines | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2004-10-07 | — | — | US | disclosed |
| US-4501834-A | POLYETHYLENE, NITROGEN CONTAINING SILANE CROSSLINKING AGENT, HYDROCARBON RESIN OR ROSIN, AND HYDROCARBON WAX | COLGATE-PALMOLIVE COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4332779-A | Phosphoric acid filtration process | AMERICAN CYANAMID COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040199018-A1 | Bridged p-phenylenediamines | COXFA4L2, CYC1, COXFA4 | TGFBR1 2418/4885TDP1 3111/4885LAP3 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.