Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1147617 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL51202 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL8192900 | 1.00 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL6889911 | 0.97 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL18140862 | 0.97 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL10621537 | 0.97 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL11626397 | 0.97 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL22499956 | 0.95 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL11663999 | 0.95 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 | |
| Biphenyl SCHEMBL11709188 | 0.95 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2L3MBTL1MAPTSLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7014925-B2 | Heterogeneous spiro compounds in organic light emitting device elements | CANON KABUSHIKI KAISHA (JP) | 2006-03-21 | — | — | US | disclosed |
| US-20040219386-A1 | Heterogeneous spiro compounds in organic light emitting device elements | CANON KABUSHIKI KAISHA (JP) | 2004-11-04 | — | — | US | disclosed |
| US-5487848-A | Preparation of difunctional initiators for anionic polymerization | XEROX CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5410013-A | Thiophene-containing poly(arylene ether) sulfones | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1995-04-25 | — | — | US | disclosed |
| US-4390736-A | FROM BENZOIC ACIDS USING OXIDE CATALYSTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040219386-A1 | Heterogeneous spiro compounds in organic light emitting device elements | OSTC, TRPA1, OCIAD1 | ALDH1A1 235/4885SMN1; SMN2 3304/4885L3MBTL1 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.