Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.66 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.43 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.43 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 5/20 | 0.43 |
| ▸ | PSMB3 | P49720 | 5/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 5/20 | 0.43 |
| ▸ | PSMA6 | P60900 | 5/20 | 0.43 |
| ▸ | PSMA8 | Q8TAA3 | 5/20 | 0.43 |
| ▸ | PSMB7 | Q99436 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26056992 | 0.86 | CES2 (0.66) | CES2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3920354 | 0.83 | CES2 (0.66) | CES2PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL5362040 | 0.83 | CES2 (0.66) | CES2PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL5357587 | 0.83 | CES2 (0.66) | CES2PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL26020578 | 0.83 | CES2 (0.43) | CES2ALDH1A1POLQHSP90AB1TMPRSS4 | |
| SCHEMBL24450665 | 0.83 | MEN1 (0.47) | CES2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL311232 | 0.83 | CES2 (0.47) | CES2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28233849 | 0.81 | CES2 (0.46) | CES2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL27920621 | 0.81 | KDM4E (0.51) | CES2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL27643680 | 0.81 | JAK2 (0.50) | CES2MAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | MEZA TOLEDO SERGIO E | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287397-A1 | Dl-hydroxy-alkyl-phenylamides having anticonvulsive activity | GABRB2, HRH3, HRH4 | CES2 146/4885PSMB11 3443/4885PSMA7 3821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.