Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA5A | P35218 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | MMP1 | P03956 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
| ▸ | MMP8 | P22894 | 1/20 | 0.62 |
| ▸ | MMP13 | P45452 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 3/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27930192 | 0.95 | KMT2A (0.66) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL28145926 | 0.92 | KMT2A (0.62) | KMT2AGAAHTTCA2CA5A | |
| Phenol SCHEMBL28105825 | 0.89 | KMT2A (0.58) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL1416363 | 0.85 | KMT2A (0.68) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL9580710 | 0.84 | KMT2A (1.00) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL28091856 | 0.83 | KMT2A (0.65) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL205255 | 0.82 | KMT2A (0.75) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL2872110 | 0.82 | KMT2A (0.64) | KMT2AGAAHTTCA2CA5A | |
| SCHEMBL15689650 | 0.82 | KMT2A (0.64) | KMT2AGAAHTTCA2CA5A | |
| Ethane SCHEMBL21001656 | 0.81 | KMT2A (0.68) | KMT2AGAAHTTCA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801045-B | Preparation method of 2-nitro-4-methylsulfonyl benzoic acid | 北京颖泰嘉和生物科技股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-113801045-B | Preparation method of 2-nitro-4-methylsulfonyl benzoic acid | 北京颖泰嘉和生物科技股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| EP-3674302-B1 | 1H-PYRROLO[2,3-C]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-C]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS | INCYTE HOLDINGS CORP (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-217409988-U | Centrifugal filter device for producing 2-nitro-4-methylsulfonylbenzoic acid | 倍合德华强(连云港)医药化工科技有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-108017479-B | Method for producing aromatic compound | 东曹株式会社 | 2022-07-29 | — | — | CN | disclosed |
| EP-3939968-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | Medicinal Bioconvergence Research Center (KR) | 2022-01-19 | — | — | EP | disclosed |
| CN-213760791-U | A separator that is used for 2-nitro-4 methylsulfonyl benzoic acid production to mix with raw materials | 倍合德华强(连云港)医药化工科技有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112601752-A | Novel inhibitors of MAP4K1 | 伊克诺斯科学公司 | 2021-04-02 | — | — | CN | disclosed |
| EP-3630778-A1 | NOVEL INHIBITORS OF MAP4K1 | Ichnos Sciences SA (CH) | 2020-04-08 | — | — | EP | disclosed |
| CN-110256308-A | Synthesis process of mesotrione | 湖北广富林生物制剂有限公司 | 2019-09-20 | — | — | CN | disclosed |
| EP-1803709-A1 | PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2007-07-04 | — | — | EP | disclosed |
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| CN-1039492-C | Herbicides | ZENECA LTD (GB) | 1998-08-12 | — | — | CN | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| CN-1095066-A | Weedicide | ZENECA LTD (GB) | 1994-11-16 | — | — | CN | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
| US-4036838-A | Process for the production of nitro derivatives of aromatic compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | KMT2A 1449/4885GAA 4203/4885HTT 4445/4885 |
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | KMT2A 1509/4885GAA 2422/4885HTT 2367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.