Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 7/20 | 0.32 |
| ▸ | ARG2 | P78540 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899650 | 0.90 | SLC6A2 (0.33) | SLC6A2SLC6A4 | |
| SCHEMBL5899762 | 0.81 | ARG1 (0.34) | ALDH1A1SLC6A2SLC6A4ARG1ARG2 | |
| SCHEMBL5899625 | 0.80 | GRM2 (0.32) | — | |
| SCHEMBL5899752 | 0.78 | TAAR1 (0.41) | ALDH1A1 | |
| SCHEMBL5899581 | 0.78 | GRM2 (0.33) | — | |
| SCHEMBL5899778 | 0.75 | ARG1 (0.31) | ALDH1A1ARG1ARG2 | |
| SCHEMBL5899786 | 0.75 | EPHX2 (0.46) | EPHX2ARG1ARG2 | |
| SCHEMBL3546456 | 0.73 | GRM2 (0.35) | SLC6A2SLC6A4 | |
| SCHEMBL5899606 | 0.71 | CPB2 (0.31) | — | |
| SCHEMBL5899728 | 0.70 | BLM (0.42) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030267-B2 | Cycloproply β-amino acid derivatives | WARNER-LAMBERT COMPANY, LLC (US) | 2006-04-18 | — | — | US | disclosed |
| US-20040147608-A1 | Cyclopropyl beta-amino acid derivatives | SCHWARZ JACOB BRADLEY (US) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147608-A1 | Cyclopropyl beta-amino acid derivatives | CACNA1S, CACNA1D, CACNA1B | ALDH1A1 1295/4885EPHX2 2475/4885SLC6A2 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.