Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dichloroethane SCHEMBL7491055 | 1.00 | TSHR (0.62) | TSHRALDH1A1TDP1HSD17B10MAPT | |
| 1,2-Dichloroethane SCHEMBL504638 | 1.00 | — | — | |
| 1,2-Dichloroethane SCHEMBL3406969 | 0.94 | — | — | |
| 1,2-Dichloroethane SCHEMBL6360893 | 0.82 | — | — | |
| Chloroform SCHEMBL9644858 | 0.82 | TSHR (0.42) | TSHRALDH1A1TDP1LMNATP53 | |
| 1,2-Dichloroethane SCHEMBL28166518 | 0.82 | TSHR (0.50) | TSHRALDH1A1TDP1TP53 | |
| Methylene Chloride SCHEMBL992285 | 0.80 | ALDH1A1 (0.57) | TSHRALDH1A1TDP1HSD17B10 | |
| Methylene Chloride SCHEMBL1832445 | 0.80 | ALDH1A1 (0.57) | TSHRALDH1A1TDP1HSD17B10 | |
| Methylene Chloride SCHEMBL9625167 | 0.80 | ALDH1A1 (0.57) | TSHRALDH1A1TDP1HSD17B10 | |
| Methylene Chloride SCHEMBL2031974 | 0.80 | ALDH1A1 (0.57) | TSHRALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019110-B2 | Streptogramin derivatives, preparation method and compositions containing same | AVENTIS PHARMA S.A. (FR) | 2006-03-28 | — | — | US | disclosed |
| US-4329347-A | Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril | BOEHRINGER INGELHEIM GMBH (DE) | 1982-05-11 | — | — | US | disclosed |