Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | C1S | P09871 | 2/20 | 0.35 |
| ▸ | GPR6 | P46095 | 6/20 | 0.34 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL15400550 | 0.85 | GPR6 (0.37) | MEN1HTTKMT2AC1SGPR6 | |
| Trifluoroacetic Acid SCHEMBL2672176 | 0.82 | GPR6 (0.36) | MEN1HTTKMT2AC1SGPR6 | |
| Trifluoroacetic Acid SCHEMBL588532 | 0.81 | KMT2A (0.36) | MEN1HTTKMT2AC1SGPR6 | |
| Trifluoroacetic Acid SCHEMBL589653 | 0.76 | FFAR1 (0.34) | C1SGPR6DPP4DPP7CCR1 | |
| Trifluoroacetic Acid SCHEMBL589654 | 0.76 | FFAR1 (0.34) | C1SGPR6DPP4DPP7CCR1 | |
| Trifluoroacetic Acid SCHEMBL589362 | 0.76 | FFAR1 (0.34) | C1SGPR6DPP4DPP7CCR1 | |
| Trifluoroacetic Acid SCHEMBL589361 | 0.76 | FFAR1 (0.34) | C1SGPR6DPP4DPP7CCR1 | |
| Trifluoroacetic Acid SCHEMBL589894 | 0.75 | C1S (0.42) | MEN1KMT2AC1SGPR6SCN9A | |
| Trifluoroacetic Acid SCHEMBL2672126 | 0.74 | C1S (0.32) | C1S | |
| SCHEMBL3702612 | 0.74 | HRH4 (0.39) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114878-B2 | 6,7-dihydrothieno[3,2-d]pyrimidine for the treatment of inflammatory diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-14 | — | — | US | disclosed |