Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714230 | 0.81 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1PGRGAAPTGS1 | |
| SCHEMBL30003172 | 0.81 | ALOX15 (0.50) | NCEH1LMNAMAPTALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27504502 | 0.80 | ALDH1A1 (0.58) | LMNAL3MBTL1ALDH1A1PGRGAA | |
| SCHEMBL28694838 | 0.79 | ALDH1A1 (0.50) | NCEH1MAPTL3MBTL1ALDH1A1PGR | |
| SCHEMBL20398569 | 0.79 | ELANE (0.50) | LMNAMAPTALOX15CYP1A2CYP2C9 | |
| SCHEMBL9488962 | 0.78 | HTT (0.54) | NCEH1LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL10344381 | 0.78 | NCEH1 (0.43) | NCEH1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10440127 | 0.77 | ALDH1A1 (0.56) | NCEH1LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL29728557 | 0.77 | NCEH1 (0.55) | NCEH1LMNAMAPTALDH1A1PGR | |
| SCHEMBL16965708 | 0.77 | NCEH1 (0.55) | NCEH1LMNAMAPTALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211684-A1 | Use of alpha-2 adrenergic receptor agonists | PERLEGEN SCIENCES, INC. (US) | 2006-09-21 | — | — | US | disclosed |