Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17958929 | 0.86 | TDP1 (0.54) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL7289598 | 0.83 | MAPT (0.60) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL27703867 | 0.82 | L3MBTL1 (0.63) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL34466860 | 0.82 | TDP1 (0.56) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL12921043 | 0.82 | TDP1 (0.56) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL701961 | 0.81 | MAPT (1.00) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL29633530 | 0.81 | MAPT (1.00) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL21483694 | 0.80 | L3MBTL1 (0.56) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL7855165 | 0.79 | MAPT (0.71) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL30591972 | 0.78 | PTGDR2 (0.67) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036901-B1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2013-05-01 | — | — | EP | disclosed |
| US-8115017-B2 | C-phenyl 1-thioglucitol compound | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2012-02-14 | — | — | US | disclosed |
| US-7973012-B2 | C-phenyl glycitol compound | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-20100022460-A1 | C-PHENYL GLYCITOL COMPOUND | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20100004465-A1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2103607-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-09-23 | — | — | EP | disclosed |
| EP-2036901-A1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022460-A1 | C-PHENYL GLYCITOL COMPOUND | SLC5A1, SLC5A2, SLC2A1 | MAPT 1940/4885TDP1 4824/4885L3MBTL1 1761/4885 |
| US-20100004465-A1 | C-PHENYL 1-THIOGLUCITOL COMPOUND | SLC5A1, SLC5A2, SLC2A1 | MAPT 1989/4885TDP1 3815/4885L3MBTL1 3293/4885 |
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | MAPT 583/4885TDP1 1126/4885L3MBTL1 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.