Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27436030 | 0.89 | L3MBTL1 (0.53) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL7289598 | 0.82 | MAPT (0.60) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL590545 | 0.80 | MAPT (0.68) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL34466860 | 0.79 | TDP1 (0.56) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL12921043 | 0.79 | TDP1 (0.56) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL6552022 | 0.77 | MAPT (0.54) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL7064594 | 0.77 | FOLH1 (0.55) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL9679320 | 0.77 | MAPT (0.60) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL9123233 | 0.76 | MAPT (0.71) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 | |
| SCHEMBL1106947 | 0.75 | MAOB (0.61) | L3MBTL1TDP1MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3556435-B1 | CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE | BEIJING SHOWBY PHARMACEUTICAL CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| EP-3556435-A1 | CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE | Beijing Showby Pharmaceutical Co., Ltd. (CN) | 2019-10-23 | — | — | EP | disclosed |