Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 5/20 | 1.00 |
| ▸ | DRD2 | P14416 | 6/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.62 |
| ▸ | HTR1A | P08908 | 4/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.62 |
| ▸ | DRD1 | P21728 | 4/20 | 0.62 |
| ▸ | DRD3 | P35462 | 4/20 | 0.62 |
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | HTR2C | P28335 | 4/20 | 0.62 |
| ▸ | HRH1 | P35367 | 4/20 | 0.62 |
| ▸ | HTR2B | P41595 | 4/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490256 | 0.87 | SETD7 (0.76) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL11573091 | 0.87 | SETD7 (0.76) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL11576560 | 0.87 | SETD7 (0.76) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| Clopipazan SCHEMBL1816896 | 0.87 | SETD7 (0.76) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL11575486 | 0.85 | SETD7 (0.72) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| Azanator SCHEMBL2110669 | 0.84 | SETD7 (0.71) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL9208700 | 0.84 | SETD7 (0.71) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL3384621 | 0.84 | SETD7 (0.71) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL11574720 | 0.84 | SETD7 (0.70) | SETD7DRD2CHRM2CHRM1ADRA1A | |
| SCHEMBL11576021 | 0.84 | SETD7 (0.70) | SETD7DRD2CHRM2CHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111342-A1 | Insecticidal tricyclic derivatives | BAYER CROPSCIENCE AG (DE) | 2006-05-25 | — | — | US | disclosed |
| EP-1538906-A2 | INSECTICIDAL TRICYCLIC DERIVATIVES | FMC CORPORATION (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004026030-A2 | INSECTICIDAL TRICYCLIC DERIVATIVES | FMC CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |
| US-5416087-A | Bis-benzo, cyclohepta piperidylidene, piperidine and piperazine compounds, compositions and methods of use | SCHERING CORPORATION | 1995-05-16 | — | — | US | disclosed |
| EP-0552245-A1 | BIS-BENZO CYCLOHEPTA PIPERIDYLIDENE, PIPERIDINE AND PIPERAZINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1993-07-28 | — | — | EP | disclosed |
| WO-1992006970-A1 | BIS-BENZO CYCLOHEPTA PIPERIDYLIDENE, PIPERIDINE AND PIPERAZINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | SCHERING CORPORATION (US) | 1992-04-30 | — | — | WO | disclosed |
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111342-A1 | Insecticidal tricyclic derivatives | DDT, ACHE, ODC1 | SETD7 1641/4885DRD2 368/4885CHRM2 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.