Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905848 | 1.00 | CES1 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL11365790 | 0.78 | CES2 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL16933770 | 0.78 | CES2 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL9194347 | 0.78 | CES2 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL1792813 | 0.76 | AKT1 (0.41) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL16634441 | 0.76 | MAPT (0.44) | ALDH1A1TSHRMAPK1PTPN1CYP3A4 | |
| SCHEMBL1792814 | 0.76 | AKT1 (0.41) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL1444874 | 0.74 | ALDH1A1 (0.43) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL11496472 | 0.74 | CES1 (0.36) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL4456359 | 0.74 | AKR1C1 (0.50) | ALDH1A1TSHRMAPK1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049268-A1 | Flame retardant molding compositions having improved flow | WHITE ROGER J (US) | 2002-04-25 | — | — | US | claimed |
| CN-115197046-B | Halogenation method of unsaturated hydrocarbon | 华南理工大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115197046-A | Halogenation method of unsaturated hydrocarbon | 华南理工大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-109265325-A | A kind of bis- bromo alkenes compounds of 1,2- and its preparation method and application | 广东工业大学 | 2019-01-25 | — | — | CN | disclosed |
| CN-108129260-A | A kind of synthetic method of styrene glycol | 常州南京大学高新技术研究院 | 2018-06-08 | — | — | CN | disclosed |
| CN-107754860-A | A kind of catalyst, preparation method and applications for preparing the ethylene glycol of 1 phenyl 1,2 from styrene for one kettle way | 上海应用技术大学 | 2018-03-06 | — | — | CN | disclosed |
| WO-2006110697-A2 | SYNTHESIS OF HYDROXYLATED HYDROCARBONS | GRT, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| US-20060229475-A1 | Synthesis of hydroxylated hydrocarbons | REACTION 35, LLC | 2006-10-12 | — | — | US | disclosed |
| EP-1426412-A2 | Impact modified thermoplastic polycarbonate molding composition | Bayer Corporation (US) | 2004-06-09 | — | — | EP | disclosed |
| US-20030212116-A1 | Heterocyclic imino compounds and fungicides and insecticides for agricultural and horitcultural use | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-13 | — | — | US | disclosed |
| EP-0135904-B1 | POLYETHYLENE TEREPHTHALATE/POLYCARBONATE BLENDS HAVING A LOW LEVEL OF WARPAGE | MOBAY CORPORATION (US) | 1987-07-29 | — | — | EP | disclosed |
| EP-0108996-B1 | THERMOPLASTIC RESINOUS BLEND HAVING AN IMPROVED IMPACT PERFORMANCE | MOBAY CORPORATION (US) | 1986-09-10 | — | — | EP | disclosed |
| US-4554314-A | Thermoplastic molding compositions | MOBAY CHEMICAL CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |
| US-4554315-A | POLYESTER, POLYCARBONATE, GRAFT POLYMER, POLYMERIC EPOXIDE | MOBAY CHEMICAL CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |
| US-4551502-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square platinous and equivalent organometallics | HOWELL BOBBY A | 1985-11-05 | — | — | US | disclosed |
| EP-0135904-A2 | Polyethylene terephthalate/polycarbonate blends having a low level of warpage | MOBAY CORPORATION (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4487881-A | ACRYLONITRILE-BUTADIENE- STYRENE TERPOLYMER A MALEIC ANHYDRIDE COPOLYMER AND GLASS FIBERS | MOBAY CHEMICAL CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |
| US-4466912-A | FLAKES IN BLEND OF POLYCARBONATE AND AN ABS GRAFT TERPOLYMER | MOBAY CHEMICAL CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| EP-0108996-A1 | Thermoplastic resinous blend having an improved impact performance | MOBAY CORPORATION (US) | 1984-05-23 | — | — | EP | disclosed |
| US-4405757-A | Macromolecular complexes of amidocarbonylic water-soluble polymers and square planar platinous and equivalent organometallics | HOWELL BOBBY A | 1983-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212116-A1 | Heterocyclic imino compounds and fungicides and insecticides for agricultural and horitcultural use | DDT, CBR3, CYP1B1 | CES1 1212/4885ALDH1A1 1119/4885CES2 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.