⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2884124 | 0.81 | — | — | |
| SCHEMBL18774295 | 0.79 | — | — | |
| SCHEMBL28156971 | 0.77 | DNM1 (0.55) | — | |
| SCHEMBL3131657 | 0.77 | DNM1 (0.55) | — | |
| SCHEMBL28313652 | 0.77 | DNM1 (0.55) | — | |
| SCHEMBL28157003 | 0.77 | DNM1 (0.55) | — | |
| SCHEMBL18618605 | 0.77 | DNM1 (0.55) | — | |
| SCHEMBL12639724 | 0.73 | — | — | |
| SCHEMBL2533670 | 0.72 | — | — | |
| SCHEMBL1533385 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158820-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-3808176-A1 | METHOD FOR SUPPRESSING FREEZING DAMAGE AND COMPOSITION FOR PREVENTING FREEZING DAMAGE | Kyoto University (JP) | 2021-04-21 | — | — | EP | disclosed |
| WO-2020132071-A1 | COMPOUNDS THAT INTERACT WITH THE RAS SUPERFAMILY FOR THE TREATMENT OF CANCERS, INFLAMMATORY DISEASES, RASOPATHIES, AND F1BROTIC DISEASE | SHY THERAPEUTICS. LLC (US) | 2020-06-25 | — | — | WO | disclosed |
| US-10450629-B2 | Use of novel compounds for selectively extracting rare earths from aqueous solutions including phosphoric acid and associated extraction method | COMMISSARIAT A L+ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2019-10-22 | — | — | US | disclosed |
| US-10273208-B2 | Screening methods for the binding affinity of chemical entities to biological molecules and NEDD4-1 inhibitors identified by the screening methods | NORTHWESTERN UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| EP-3068784-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-02-20 | — | — | EP | disclosed |
| US-20180142321-A1 | USE OF NOVEL COMPOUNDS FOR SELECTIVELY EXTRACTING RARE EARTHS FROM AQUEOUS SOLUTIONS INCLUDING PHOSPHORIC ACID AND ASSOCIATED EXTRACTION METHOD | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2018-05-24 | — | — | US | disclosed |
| EP-2760855-B1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AS WELL AS THEIR USE IN TREATING TYPE-2 DIABETES | MERCK SHARP & DOHME (US) | 2017-03-15 | — | — | EP | disclosed |
| WO-2017040764-A1 | THERAPEUTIC COMPOUNDS FOR PAIN AND SYNTHESIS THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2017-03-09 | — | — | WO | disclosed |
| EP-1469813-B1 | ADDITIVES AND PRODUCTS INCLUDING OLIGOESTERS | CRODA INC (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-0352072-B1 | IMPROVER END-CAPPED MULTIFUNCTIONAL VISCOSITY IMPROVER | EXXON CHEMICAL PATENTS INC. (US) | 1992-09-23 | — | — | EP | disclosed |
| EP-0369674-B1 | IMPROVED MULTIFUNCTIONAL VISCOSITY INDEX IMPROVER | EXXON CHEMICAL PATENTS INC. (US) | 1992-07-15 | — | — | EP | disclosed |
| US-5068047-A | Ethylene-propylene-maleic anhydride terpolymer degraded with oxygen as lubricants | EXXON CHEMICAL PATENTS, INC. (US) | 1991-11-26 | — | — | US | disclosed |
| WO-1991013952-A1 | IMPROVED MULTIFUNCTIONAL VISCOSITY INDEX IMPROVER-DISPERSANT ANTIOXIDANT (PT-789) | EXXON CHEMICAL PATENTS INC. (US) | 1991-09-19 | — | — | WO | disclosed |
| US-5035821-A | Ethylene copolymer endcapped with maleic anhydride, reacted with polyamine or polyol, viscosity index | EXXON CHEMICAL PATENTS INC. (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0369674-A1 | Improved multifunctional viscosity index improver | EXXON CHEMICAL PATENTS INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0352072-A1 | Improver end-capped multifunctional viscosity improver | EXXON CHEMICAL PATENTS INC. (US) | 1990-01-24 | — | — | EP | disclosed |
| EP-0352070-A1 | Improved multifunctional viscosity index improver | EXXON CHEMICAL PATENTS INC. (US) | 1990-01-24 | — | — | EP | disclosed |
| EP-0192145-A2 | Quaternary alkylamidobetain esters, process for their preparation and their use as laundry softening agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-08-27 | — | — | EP | disclosed |
| US-4438001-A | ANTISTATIC AGENTS | TAKEMOTOYUSHI CO. LTD. (JP) | 1984-03-20 | — | — | US | disclosed |