Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28157003 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL28156971 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL28313652 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL18618605 | 1.00 | DNM1 (0.55) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL18774295 | 0.97 | — | — | |
| SCHEMBL2884124 | 0.89 | — | — | |
| SCHEMBL14204636 | 0.82 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL20610877 | 0.81 | ALDH1A1 (0.61) | DNM1TSHRALDH1A1KDM5AKDM4C | |
| SCHEMBL28741216 | 0.78 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL11090614 | 0.77 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035047-A1 | BINARY COMPOSITIONS COMPRISING AN NO-DONOR AND AN A-SMASE INHIBITOR FOR THE TREATMENT OF RESPIRATORY DISEASES | PHARMAPATENTS GLOBAL LTD. (GB) | 2010-04-01 | — | — | WO | claimed |
| US-20210330822-A1 | FLUORESCENT PROBE FOR CYCLOOXYGENASE-2 | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-10-28 | — | — | US | disclosed |
| US-10408843-B2 | Compositions and methods for detecting S-nitrosylation and S-sulfinylation | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-09-10 | — | — | US | disclosed |
| US-20180199578-A1 | Compositions and Methods to Selectively Control Invasive Species | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2018-07-19 | — | — | US | disclosed |
| US-20170192012-A1 | COMPOSITIONS AND METHODS FOR DETECTING S-NITROSYLATION AND S-SULFINYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-07-06 | — | — | US | disclosed |
| US-20160084845-A1 | COMPOSITIONS AND METHODS FOR DETECTING S-NITROSYLATION AND S-SULFINYLATION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2016-03-24 | — | — | US | disclosed |
| US-9271915-B2 | Composition for dyeing keratin fibres comprising a direct dye bearing a disulphide/thiol function, a non-cellulose-based thickening polymer, an alkaline agent and a reducing agent | L'OREAL (FR) | 2016-03-01 | — | — | US | disclosed |
| US-20140041132-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULPHIDE/THIOL FUNCTION, A NON-CELLULOSE-BASED THICKENING POLYMER, AN ALKALINE AGENT AND A REDUCING AGENT | L'OREAL (FR) | 2014-02-13 | — | — | US | disclosed |
| WO-2010035047-A1 | BINARY COMPOSITIONS COMPRISING AN NO-DONOR AND AN A-SMASE INHIBITOR FOR THE TREATMENT OF RESPIRATORY DISEASES | PHARMAPATENTS GLOBAL LTD. (GB) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180199578-A1 | Compositions and Methods to Selectively Control Invasive Species | GUSB, ENGASE, ALPG | DNM1 1228/4885TSHR 2868/4885THRB 3294/4885 |
| US-20210330822-A1 | FLUORESCENT PROBE FOR CYCLOOXYGENASE-2 | PTGES2, PTGS2, HMOX2 | DNM1 3402/4885TSHR 4146/4885THRB 3985/4885 |
| US-20140041132-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULPHIDE/THIOL FUNCTION, A NON-CELLULOSE-BASED THICKENING POLYMER, AN ALKALINE AGENT AND A REDUCING AGENT | KRT18, DSG1, KLK5 | DNM1 4293/4885TSHR 4702/4885THRB 4410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.