Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 7/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906886 | 1.00 | KMO (0.48) | KMOMMP2MMP9ADAMTS4ITGB1 | |
| SCHEMBL5906845 | 0.91 | KMO (0.45) | KMOITGB1ITGA4KDM4EMEN1 | |
| SCHEMBL5906849 | 0.91 | KMO (0.45) | KMOITGB1ITGA4KDM4EMEN1 | |
| SCHEMBL5906602 | 0.83 | MME (0.50) | ITGB1ITGA4KDM4EMEN1MAPT | |
| SCHEMBL5906883 | 0.83 | ITGB1 (0.53) | ITGB1ITGA4KDM4EMEN1MAPT | |
| SCHEMBL5906881 | 0.83 | ITGB1 (0.53) | ITGB1ITGA4KDM4EMEN1MAPT | |
| SCHEMBL5906604 | 0.83 | MME (0.50) | ITGB1ITGA4KDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL5906878 | 0.82 | CYP1A2 (0.53) | ITGB1ITGA4KDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL5906880 | 0.82 | CYP1A2 (0.53) | ITGB1ITGA4KDM4EMEN1MAPT | |
| SCHEMBL5906670 | 0.82 | ITGB1 (0.55) | MMP9ITGB1ITGA4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-04-27 | — | — | US | disclosed |
| CN-1735598-A | Phenyl or heteroaryl amino alkane derivatives as IP receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-02-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BPHL, HRH4, HRH2 | KMO 842/4885MMP2 2733/4885MMP9 3950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.