Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748252 | 0.98 | HPGD (0.55) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL5907626 | 0.98 | HPGD (0.55) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL5907681 | 0.96 | HPGD (0.53) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL5907660 | 0.92 | HPGD (0.47) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL11890375 | 0.86 | RAB9A (0.58) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL14748218 | 0.85 | EPHX1 (0.47) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8241745 | 0.84 | EPHX1 (0.58) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL23081197 | 0.83 | HPGD (0.42) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL23081097 | 0.83 | HPGD (0.42) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL23081207 | 0.83 | HPGD (0.42) | HPGDRAB9ACYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060046286-A1 | Method for preparing optically active beta-butyrolactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |