Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748218 | 0.92 | EPHX1 (0.47) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL5907681 | 0.92 | HPGD (0.53) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL5907615 | 0.92 | HPGD (0.57) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL5907626 | 0.90 | HPGD (0.55) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL14748252 | 0.90 | HPGD (0.55) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL5067337 | 0.84 | RAB9A (0.49) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL18199497 | 0.84 | RAB9A (0.49) | HPGDCYP3A4CYP2C19RAB9ALMNA | |
| SCHEMBL21640354 | 0.82 | RAB9A (0.37) | HPGDCYP3A4CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL13448265 | 0.81 | HTR2A (0.39) | HPGDCYP3A4CYP2C19RAB9ASMYD3 | |
| SCHEMBL23520817 | 0.81 | HPGD (0.46) | HPGDCYP3A4CYP2C19RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060046286-A1 | Method for preparing optically active beta-butyrolactones | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |