Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.32 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744410 | 0.87 | MAPT (0.39) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL5907693 | 0.86 | MAPT (0.43) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9742565 | 0.86 | TSHR (0.41) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9742369 | 0.84 | TSHR (0.46) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL574287 | 0.83 | MAPT (0.44) | MAPTPRKCARECQLELANECYP3A4 | |
| SCHEMBL14672440 | 0.82 | MAPT (0.41) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL14069518 | 0.82 | MAPT (0.41) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL12560394 | 0.81 | PRKCA (0.41) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL9743513 | 0.81 | ALOX15 (0.35) | MAPT | |
| SCHEMBL9925380 | 0.79 | MAPT (0.44) | MAPTKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128252-A | Resolution of optically active esters, transesterification, lipase | CHISSO CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0384189-A2 | Optically active compound and a process for the production thereof | CHISSO CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |