Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775800 | 1.00 | MAPT (0.43) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL19899199 | 1.00 | MAPT (0.43) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL10510709 | 0.88 | PRKCA (0.41) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL15319570 | 0.83 | KDM4E (0.53) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL5907693 | 0.83 | MAPT (0.43) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL25476045 | 0.83 | MAPT (0.39) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2552726 | 0.83 | KDM4E (0.53) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL24414507 | 0.82 | MAPT (0.53) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL24414468 | 0.82 | MAPT (0.53) | MAPTKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL27399683 | 0.82 | MAPT (0.38) | MAPTKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210322358-A1 | Method for Treating Lysosomal Storage Disease | MCMASTER UNIVERSITY (CA) | 2021-10-21 | — | — | US | disclosed |
| US-11141392-B2 | Method of improving flavor of a composition of (D)-beta-hydroxybutyric acid and (D)-1,3 butanediol and use as a nutritional supplement and therapeutic agent | VitaNav, Inc. (US) | 2021-10-12 | — | — | US | disclosed |
| US-20210275474-A1 | METHOD OF IMPROVING FLAVOR OF A COMPOSITION OF (D)-BETA-HYDROXYBUTYRIC ACID AND (D)-1,3 BUTANEDIOL AND USE AS A NUTRITIONAL SUPPLEMENT AND THERAPEUTIC AGENT | VitaNav, Inc. (US) | 2021-09-09 | — | — | US | disclosed |
| EP-3843716-A1 | METHOD FOR TREATING LYSOSOMAL STORAGE DISEASE | Exerkine Corporation (CA) | 2021-07-07 | — | — | EP | disclosed |
| WO-2020041871-A1 | METHOD FOR TREATING LYSOSOMAL STORAGE DISEASE | EXERKINE CORPORATION (CA) | 2020-03-05 | — | — | WO | disclosed |