Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 16/20 | 0.55 |
| ▸ | CA9 | Q16790 | 16/20 | 0.55 |
| ▸ | CA2 | P00918 | 14/20 | 0.55 |
| ▸ | CA7 | P43166 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | GRK5 | P34947 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8810914 | 0.85 | CA12 (0.55) | CA12CA9CA2CA7CA1 | |
| SCHEMBL9471676 | 0.75 | KDM4E (0.46) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL1286764 | 0.74 | CA12 (0.96) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL8728937 | 0.74 | CA12 (0.96) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL485939 | 0.72 | CA12 (0.92) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL1138067 | 0.72 | CA12 (0.92) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL1018905 | 0.72 | CA12 (0.92) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL6049140 | 0.71 | CA12 (1.00) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL4777123 | 0.71 | CA12 (1.00) | CA12CA9CA2CA7CA1 | |
| Saccharin SCHEMBL7073018 | 0.71 | CA12 (1.00) | CA12CA9CA2CA7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058315-A1 | 2-Oxo-ethanesulfonamide derivates | ASTRAZENECA AB (SE) | 2006-03-16 | — | — | US | disclosed |
| EP-1562574-A1 | 2-OXO-ETHANESULFONAMIDE DERIVATES | Astrazeneca AB (SE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004041264-A1 | 2-OXO-ETHANESULFONAMIDE DERIVATES | ASTRAZENECA AB (SE) | 2004-05-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058315-A1 | 2-Oxo-ethanesulfonamide derivates | HSD11B1, HSD3B1, HSD11B2 | CA12 2102/4885CA9 2141/4885CA2 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.