Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518054 | 0.79 | HCAR2 (0.39) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8550931 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPK1TSHRMAPTKMT2A | |
| SCHEMBL1124105 | 0.75 | TDP1 (0.35) | TDP1PDK2 | |
| SCHEMBL7519075 | 0.73 | TDP1 (0.39) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL27565409 | 0.72 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPK1HPGDTSHR | |
| SCHEMBL10004861 | 0.72 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPK1HPGDTSHR | |
| SCHEMBL5477906 | 0.71 | ALDH1A1 (0.40) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL10559934 | 0.71 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2MAPK1HPGDTSHR | |
| SCHEMBL9091064 | 0.70 | TDP1 (0.56) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL20298329 | 0.70 | TDP1 (0.47) | TDP1HCAR2ALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060199840-A1 | Chemical derivatives and their application as antitelomerase agent | AVENTIS PHARMA S.A. (FR) | 2006-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199840-A1 | Chemical derivatives and their application as antitelomerase agent | NTPCR, DPYD, NME1 | TDP1 1249/4885HCAR2 2816/4885ALDH1A1 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.