Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743309 | 0.83 | ALDH1A1 (0.43) | ALDH1A1MAPTNPSR1MAPK1NPC1 | |
| SCHEMBL9423135 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MAPTNPSR1MAPK1NPC1 | |
| SCHEMBL1705589 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTNPSR1MAPK1NPC1 | |
| SCHEMBL4765941 | 0.78 | MAPT (0.40) | ALDH1A1MAPTNPSR1MAPK1NPC1 | |
| SCHEMBL5691129 | 0.77 | MAPT (0.43) | ALDH1A1MAPTNPSR1MAPK1NPC1 | |
| SCHEMBL5909552 | 0.77 | TDP1 (0.37) | ALDH1A1MAPTMAPK1HSD17B10KDM4E | |
| SCHEMBL10004608 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1MAPTNPSR1NPC1TP53 | |
| SCHEMBL11584237 | 0.77 | KDM4E (0.42) | ALDH1A1MAPTNPSR1NPC1TP53 | |
| SCHEMBL9590986 | 0.76 | MAPT (0.45) | ALDH1A1MAPTNPSR1MAPK1NPC1 | |
| SCHEMBL31087409 | 0.76 | MAPT (0.43) | ALDH1A1MAPTNPSR1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |