Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909589 | 0.82 | CXCL12 (0.38) | SMN1; SMN2DHFRMAPTNPSR1ALDH1A1 | |
| SCHEMBL7718121 | 0.81 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2HAO1DHFR | |
| SCHEMBL29673038 | 0.80 | MAPT (0.43) | NPC1RAB9ASMN1; SMN2HAO1DHFR | |
| SCHEMBL9627573 | 0.80 | MAPT (0.43) | NPC1RAB9ASMN1; SMN2HAO1DHFR | |
| SCHEMBL13752159 | 0.72 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2HAO1DHFR | |
| SCHEMBL8384783 | 0.71 | MAPT (0.44) | NPC1RAB9ASMN1; SMN2HAO1DHFR | |
| SCHEMBL4650764 | 0.69 | — | — | |
| SCHEMBL28177683 | 0.66 | MAPT (0.49) | NPC1MAPTNPSR1KMT2ACYP1A2 | |
| SCHEMBL12245875 | 0.65 | ACHE (0.57) | NPC1RAB9ASMN1; SMN2HAO1MAPT | |
| SCHEMBL83853 | 0.65 | ACHE (0.57) | NPC1RAB9ASMN1; SMN2HAO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060107869-A1 | Inks for digital textile printing with reactive yellow fluorescent dyes | DYSTAR TEXTILF DEUTSCHLAND KG (DE) | 2006-05-25 | — | — | US | disclosed |
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0201026-B1 | METAL COMPLEX DYES | BAYER AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4813972-A | USING LEVELING DYES, COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4772687-A | AZO DYES, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | disclosed |
| US-4723001-A | Fibre-reactive chromium complexes and their preparation and use | CIBA-GEIGY CORPORATION (US) | 1988-02-02 | — | — | US | disclosed |
| US-4678851-A | FIBER-RACTIVE | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | disclosed |
| US-4418015-A | Phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060107869-A1 | Inks for digital textile printing with reactive yellow fluorescent dyes | IK, COL1A1, DDX41 | NPC1 4150/4885RAB9A 1080/4885SMN1; SMN2 1361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.