SCHEMBL591198

SCHEMBL591198

CCCC(=O)Oc1ccc2c(C(F)(F)F)cc(=O)oc2c1

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.70
▸ ALDH1A1 P00352 1/20 0.70
▸ GLA P06280 1/20 0.70
▸ GAA P10253 1/20 0.70
▸ KMT2A Q03164 1/20 0.70
▸ AGER Q15109 2/20 0.63
▸ PABPC1 P11940 1/20 0.57
▸ TLR9 Q9NR96 1/20 0.57
▸ AR P10275 13/20 0.57
▸ HSD17B3 P37058 1/20 0.54
▸ PPARA Q07869 1/20 0.54
▸ MAOB P27338 1/20 0.54
▸ MAP2K1 Q02750 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL592851 0.92 ALDH1A1 (0.60) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL22523871 0.91 AGER (0.65) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL592765 0.87 AGER (0.54) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL593504 0.85 KDM4E (0.67) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL28444520 0.83 AR (0.67) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL145934 0.82 ALDH1A1 (1.00) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL238765 0.81 AGER (0.70) AGERARMAOB
SCHEMBL28438520 0.81 AR (0.69) AGERPABPC1TLR9ARPPARA
SCHEMBL7914329 0.81 AGER (0.60) KDM4EALDH1A1GLAGAAKMT2A
SCHEMBL7914263 0.80 AGER (0.66) KDM4EALDH1A1GAAKMT2AAGER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11150358-B2 Radiation dosimetry sol or gel and radiation dosimeter comprising same as material for radiation dosimetry RIKEN (JP) 2021-10-19 — — US disclosed
US-20200333474-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY RIKEN (JP) 2020-10-22 — — US disclosed
EP-3686632-A1 RADIATION DOSIMETRY SOL OR GEL AND RADIATION DOSIMETER COMPRISING SAME AS MATERIAL FOR RADIATION DOSIMETRY Riken (JP) 2020-07-29 — — EP disclosed
US-9631219-B2 Metabolic rate indicator for cellular populations NALCO COMPANY (US) 2017-04-25 — — US disclosed
US-9086489-B2 Personal and area self-indicating instant radiation alert dosimeter JP LABORATORIES, INC (US) 2015-07-21 — — US disclosed
US-20120181453-A1 PERSONAL AND AREA SELF-INDICATING INSTANT RADIATION ALERT DOSIMETER JP LABORATORIES INC. 2012-07-19 — — US disclosed
US-8115182-B1 Personal and area self-indicating radiation alert dosimeter JP LABORATORIES INC. 2012-02-14 — — US disclosed
US-20110207111-A1 METABOLIC RATE INDICATOR FOR CELLULAR POPULATIONS ECOLAB USA INC. 2011-08-25 — — US disclosed
US-7227158-B1 Stick-on self-indicating instant radiation dosimeter JP LABS, INC. (US) 2007-06-05 — — US disclosed
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