⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587373 | 1.00 | ADH1B (0.37) | — | |
| SCHEMBL6444757 | 1.00 | ADH1B (0.37) | — | |
| SCHEMBL27447048 | 0.97 | ADH1B (0.36) | — | |
| SCHEMBL448195 | 0.97 | — | — | |
| SCHEMBL958999 | 0.91 | — | — | |
| SCHEMBL542979 | 0.84 | — | — | |
| SCHEMBL5143 | 0.77 | CYP1A2 (0.40) | — | |
| SCHEMBL4325 | 0.77 | CYP1A2 (0.40) | — | |
| SCHEMBL5276 | 0.77 | — | — | |
| SCHEMBL866288 | 0.77 | CYP1A2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112154147-A | Substituted phenylthiouracils, their salts and their use as herbicides | 先正达农作物保护股份公司 | 2020-12-29 | — | — | CN | claimed |
| US-11939345-B2 | Physiologically stable fluorophore and performing fluorescence probing | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (US) | 2024-03-26 | — | — | US | disclosed |
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |
| US-20210179653-A1 | REDOX REVERSIBLE FLUORESCENT PROBE AND PERFORMING SINGLE-ELECTRON TRANSFER FLUORESCENCE PROBING | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE | 2021-06-17 | — | — | US | disclosed |
| US-20210179639-A1 | PHYSIOLOGICALLY STABLE FLUOROPHORE AND PERFORMING FLUORESCENCE PROBING | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE | 2021-06-17 | — | — | US | disclosed |
| CN-108752241-B | Acylguanidines for the treatment of arthrosis | 默克专利股份公司 | 2021-03-12 | — | — | CN | disclosed |
| CN-105102424-B | Acylguanidines for the treatment of arthrosis | 默克专利股份公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20200031778-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-30 | — | — | US | disclosed |
| EP-3519389-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2019-08-07 | — | — | EP | disclosed |
| WO-2018060091-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLYLMETHYL DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-05 | — | — | WO | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| EP-0640082-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-03-01 | — | — | EP | disclosed |
| US-5338844-A | 2-substituted-2-cyclopentenone compound and anticancer agent and bone formation accelerator comprising same as active ingredient | TEIJIN LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5318959-A | A new miticides diaryl alkyl 1,2,4-triazoles | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| CN-1079221-A | New triazole derivative and sterilant and miticide | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1993-12-08 | — | — | CN | disclosed |
| EP-0572142-A2 | Novel 3,5-diphenyl substituted 1,2,4-triazoles and their use as insecticides and acaricides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
| WO-1993023395-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | KABI PHARMACIA AB (SE) | 1993-11-25 | — | — | WO | disclosed |
| US-5216183-A | Antitumor, anticarcinogenic agents; bone formation accelerators | TEIJIN LIMITED (JP) | 1993-06-01 | — | — | US | disclosed |
| EP-0448726-A1 | 2-SUBSTITUTED 2-CYCLOPENTENONE AND CARCINOSTATIC AGENT AND OSTEOGENESIS PROMOTER CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1991-10-02 | — | — | EP | disclosed |
| WO-1989001932-A1 | 2-ALKYL AND 2-ALKENYL SUBSTITUTED 1,4-DIHYDROPYRIDINES, A METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-03-09 | — | — | WO | disclosed |