Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.53 |
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | CALML3 | P27482 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SDHA | P31040 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591440 | 1.00 | MAOB (0.53) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL6918139 | 0.90 | MAOB (0.53) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL13232270 | 0.88 | MAOB (0.52) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL12950996 | 0.85 | MAOA (0.72) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL13034192 | 0.85 | MAOA (0.72) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL6097822 | 0.85 | MAOA (0.72) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL1222864 | 0.85 | CALML3 (0.52) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL1222866 | 0.85 | CALML3 (0.52) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL592028 | 0.84 | F10 (0.53) | MAOBMAOACALML3LMNAPTGS1 | |
| SCHEMBL1222787 | 0.84 | CALML3 (0.67) | MAOBMAOACALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146987-B1 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8114867-B2 | Oxazolidinone antibiotic derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-14 | — | — | US | disclosed |
| US-20100137290-A1 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD. (CH) | 2010-06-03 | — | — | US | disclosed |
| EP-2146987-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008126024-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137290-A1 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | OXA1L, XDH, CCNY | MAOB 240/4885MAOA 1070/4885CALML3 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.